BTN1A1 and XDH

Number of citations of the paper that reports this interaction (PubMedID 12456835)
34

Data Source:
HPRD (in vivo)

		BTN1A1	XDH
Description		butyrophilin subfamily 1 member A1	xanthine dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Space Peroxisome Cytosol Sarcoplasmic Reticulum
	Molecular Function	Signaling Receptor Binding Protein Binding Signaling Receptor Activity	Xanthine Dehydrogenase Activity Xanthine Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Protein Homodimerization Activity Molybdopterin Cofactor Binding Flavin Adenine Dinucleotide Binding 2 Iron, 2 Sulfur Cluster Binding Hypoxanthine Dehydrogenase Activity Hypoxanthine Oxidase Activity FAD Binding
	Biological Process	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway	Allantoin Metabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Endothelial Cell Proliferation Guanine Catabolic Process Inosine Catabolic Process Deoxyinosine Catabolic Process Adenosine Catabolic Process Deoxyadenosine Catabolic Process Deoxyguanosine Catabolic Process AMP Catabolic Process IMP Catabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Lactation Hypoxanthine Catabolic Process Xanthine Catabolic Process Negative Regulation Of Gene Expression Iron-sulfur Cluster Assembly Negative Regulation Of Endothelial Cell Differentiation GMP Catabolic Process DGMP Catabolic Process DAMP Catabolic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Vasculogenesis
Pathways		Butyrophilin (BTN) family interactions	Purine catabolism Butyrophilin (BTN) family interactions
Drugs			Allopurinol Levocarnitine Topiroxostat Flavin adenine dinucleotide Dioxo(sulfanyl)molybdenum Eniluracil Niraxostat Febuxostat Oxypurinol
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Body mass index ( 28552196) Brain morphology (MOSTest) ( 32665545) Educational attainment (years of education) ( 23722424) Fish- and plant-related diet ( 32066663) Gastroesophageal reflux disease ( 34187846 31527586) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Iron status biomarkers ( 19084217) Liver iron content ( 34128465) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Weight ( 28552196)	Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Male-pattern baldness ( 28196072) Multiple system atrophy ( 27629089) Obesity-related traits ( 23251661) Parahippocampal gyrus volume ( 31530798) Periventricular white matter hyperintensities ( 32517579) Zinc levels ( 26025379)
Interacting Genes		3 interacting genes: MEOX2 MOSPD2 XDH	2 interacting genes: BTN1A1 GRIP1
Entrez ID		696	7498
HPRD ID		03365	06363
Ensembl ID		ENSG00000124557	ENSG00000158125
Uniprot IDs		Q13410 Q4VAN2	P47989
PDB IDs			2CKJ 2E1Q
Enriched GO Terms of Interacting Partners?
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