SYN1 and RB1CC1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
8

Data Source:
BioGRID (two hybrid)

		SYN1	RB1CC1
Description		synapsin I	RB1 inducible coiled-coil 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Golgi Apparatus Cytosol Cytoskeleton Synaptic Vesicle Postsynaptic Density Axon Dendrite Synaptic Vesicle Membrane Presynaptic Active Zone Schaffer Collateral - CA1 Synapse Extrinsic Component Of Synaptic Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Actin Binding Transporter Activity ATP Binding Protein Kinase Binding Identical Protein Binding Calcium-dependent Protein Binding	Protein Binding Protein Kinase Binding Molecular Adaptor Activity
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Regulation Of Neurotransmitter Secretion Neuron Development Synapse Organization Synaptic Vesicle Clustering Regulation Of Synaptic Vesicle Cycle Regulation Of Synaptic Vesicle Exocytosis	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Sensory processing of sound by inner hair cells of the cochlea	Macroautophagy
Drugs		Adenosine 5'-[gamma-thio]triphosphate
Diseases
GWAS			Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		30 interacting genes: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 PAK2 PAK3 PFN2 PIK3R1 PLCG1 PRKACA RASA1 RB1CC1 S100A1 SNCA SPTAN1 SRC SYN2 SYN3 VIM	33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1
Entrez ID		6853	9821
HPRD ID		02433	06019
Ensembl ID		ENSG00000008056	ENSG00000023287
Uniprot IDs		P17600	Q8TDY2
PDB IDs			6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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