SYN1 and SYN2

Number of citations of the paper that reports this interaction (PubMedID 10358015)
31

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SYN1	SYN2
Description		synapsin I	synapsin II
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Golgi Apparatus Cytosol Cytoskeleton Synaptic Vesicle Postsynaptic Density Axon Dendrite Synaptic Vesicle Membrane Presynaptic Active Zone Schaffer Collateral - CA1 Synapse Extrinsic Component Of Synaptic Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Plasma Membrane Postsynaptic Density Synaptic Vesicle Membrane SNARE Complex Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Actin Binding Transporter Activity ATP Binding Protein Kinase Binding Identical Protein Binding Calcium-dependent Protein Binding	ATP Binding Identical Protein Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Regulation Of Neurotransmitter Secretion Neuron Development Synapse Organization Synaptic Vesicle Clustering Regulation Of Synaptic Vesicle Cycle Regulation Of Synaptic Vesicle Exocytosis	Chemical Synaptic Transmission Neurotransmitter Secretion Calcium-ion Regulated Exocytosis Synaptic Vesicle Clustering
Pathways		Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Sensory processing of sound by inner hair cells of the cochlea	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
Drugs		Adenosine 5'-[gamma-thio]triphosphate
Diseases
GWAS			Body shape index ( 34021172) Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Creatinine levels ( 29403010) Eosinophil counts ( 32888494) Estimated glomerular filtration rate ( 31152163) Fasting blood insulin (BMI interaction) ( 22581228) Glomerular filtration rate ( 29403010) Glycated hemoglobin levels ( 34059833 28898252) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Leprosy ( 27976721) Nontraumatic osteonecrosis of the femoral head ( 32701715) Platelet count ( 22139419 29403010) Thyroid stimulating hormone levels ( 32769997 25743335) Triglycerides ( 30275531) Type 2 diabetes ( 18372903) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		30 interacting genes: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 PAK2 PAK3 PFN2 PIK3R1 PLCG1 PRKACA RASA1 RB1CC1 S100A1 SNCA SPTAN1 SRC SYN2 SYN3 VIM	7 interacting genes: CHRM4 NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ
Entrez ID		6853	6854
HPRD ID		02433	02857
Ensembl ID		ENSG00000008056	ENSG00000157152
Uniprot IDs		P17600	B3KRB3 Q59GM1 Q86VA8 Q92777
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?