STX5 and NSFL1C

Number of citations of the paper that reports this interaction (PubMedID 9506515)
94

Data Source:
HPRD (in vitro)

		STX5	NSFL1C
Description		syntaxin 5	NSFL1 cofactor
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	RHOH GTPase cycle
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		51 interacting genes: AARD APLP1 AQP6 BAG6 BET1 CCDC153 COPS6 CRB3 CREB3L3 EBP FAM209A GET3 GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STX8 STXBP1 TACC1 TMEM31 TP53 USO1 VAMP5 VAPB VCP VCPIP1	17 interacting genes: ANP32A CDK1 DBI FAM32A FASTKD5 GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP
Entrez ID		6811	55968
HPRD ID		04426	09425
Ensembl ID		ENSG00000162236	ENSG00000088833
Uniprot IDs		B4DKR0 Q13190	Q53FE8 Q9UNZ2
PDB IDs		3EFO	1SS6
Enriched GO Terms of Interacting Partners?
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