NSFL1C and TARDBP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NSFL1C	TARDBP
Description		NSFL1 cofactor	TAR DNA binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasmic Stress Granule Nuclear Speck Interchromatin Granule
	Molecular Function	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Double-stranded DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Negative Regulation Of Protein Phosphorylation MRNA Processing RNA Splicing Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Protein Stability Positive Regulation Of Insulin Secretion Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Import Into Nucleus Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Negative Regulation By Host Of Viral Transcription Rhythmic Process Regulation Of Cell Cycle 3'-UTR-mediated MRNA Destabilization 3'-UTR-mediated MRNA Stabilization Nuclear Inner Membrane Organization
Pathways		RHOH GTPase cycle
Drugs
Diseases
GWAS			Beard thickness ( 26926045) Ewing sarcoma ( 22327514) Male-pattern baldness ( 22693459 28196072)
Interacting Genes		17 interacting genes: ANP32A CDK1 DBI FAM32A FASTKD5 GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP	16 interacting genes: APP EXOSC10 FBXO7 FCGR2A IRAK2 LSM6 MED6 NACC1 NSFL1C RACK1 RNF2 SETDB1 UBQLN1 XRN2 ZFAND2B ZHX1
Entrez ID		55968	23435
HPRD ID		09425	05466
Ensembl ID		ENSG00000088833	ENSG00000120948
Uniprot IDs		Q53FE8 Q9UNZ2	A0A024R4E2 Q13148 Q9H256
PDB IDs		1SS6	1WF0 2CQG 2N2C 2N3X 2N4G 2N4H 2N4P 4BS2 4IUF 4Y00 4Y0F 5MDI 5MRG 5W50 5W52 5W7V 5WHN 5WHP 5WIA 5WIQ 5WKB 5WKD 5X4F 6B1G 6CF4 6CFH 6N37 6N3A 6N3B 6N3C 6T4B 7KWZ
Enriched GO Terms of Interacting Partners?
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