STC1 and MAT2B

		STC1	MAT2B
Description		stanniocalcin 1	methionine adenosyltransferase 2B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Apical Plasma Membrane	Nucleus Cytosol Methionine Adenosyltransferase Complex Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding Identical Protein Binding	Protein Binding Enzyme Binding Methionine Adenosyltransferase Regulator Activity
	Biological Process	Ossification Endothelial Cell Morphogenesis Growth Plate Cartilage Axis Specification Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Response To Vitamin D Chondrocyte Proliferation Regulation Of Anion Transport Decidualization Negative Regulation Of Calcium Ion Transport Bone Development Cellular Response To CAMP Cellular Response To Glucocorticoid Stimulus Cellular Response To Hypoxia Regulation Of Cardiac Muscle Cell Contraction Positive Regulation Of Calcium Ion Import Negative Regulation Of Renal Phosphate Excretion	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Regulation Of Catalytic Activity
Pathways			Methylation Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood urea nitrogen levels ( 31152163 29403010) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Kidney volume ( 34128465) Serum uric acid levels ( 30993211) Subcutaneous adipose tissue ( 22589738) Urate levels ( 31985003 31578528 23263486) Urinary albumin-to-creatinine ratio ( 31511532) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Age at first sexual intercourse ( 34211149) Aging ( 22773346) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Broad depression or major depressive disorder (self-reported) ( 30626913) Chronotype ( 30696823) Common carotid intima-media thickness ( 29206233) General risk tolerance (MTAG) ( 30643258) Methadone dose in opioid dependence ( 28115739) Neuritic plaque ( 31497858) Number of sexual partners ( 30643258) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Smoking initiation ( 24665060) Uterine fibroid size (maximum dimension) ( 30196971) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		3 interacting genes: MAT2B MEOX2 NOTCH1	16 interacting genes: APP CNIH4 FBXO25 GABRA1 HRH1 KPNA3 KPNA4 MAT2A MSX2 PLA2G6 RABEP1 STC1 TEPSIN TMED9 TRIM27 YTHDF3
Entrez ID		6781	27430
HPRD ID		03115	05701
Ensembl ID		ENSG00000159167	ENSG00000038274
Uniprot IDs		P52823	A0A140VJP2 Q9NZL9
PDB IDs			2YDX 2YDY 4KTT 4KTV 4NDN
Enriched GO Terms of Interacting Partners?
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