SRP72 and FCHSD2

Number of citations of the paper that reports this interaction (PubMedID 18654987)
21

Data Source:
BioGRID (two hybrid)

		SRP72	FCHSD2
Description		signal recognition particle 72	FCH and double SH3 domains 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding TPR Domain Binding Ribosome Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)	Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 33272962 26663301)
Interacting Genes		13 interacting genes: CASP3 CASP6 CDC42 EDN2 FCHSD2 HSPB1 KDR OGT PYGM SKIL SRP68 SULT2B1 TULP3	53 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE2A PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		6731	9873
HPRD ID		03671	13321
Ensembl ID		ENSG00000174780	ENSG00000137478
Uniprot IDs		O76094 V9HWK0	O94868
PDB IDs		5M72 5M73 5WRV 5WRW	2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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