FUNDC2 and ARL15

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FUNDC2	ARL15
Description		FUN14 domain containing 2	ADP ribosylation factor like GTPase 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane	Extracellular Exosome
	Molecular Function	Protein Binding	Molecular_function GTPase Activity Protein Binding GTP Binding
	Biological Process	Autophagy Of Mitochondrion	Biological_process
Pathways
Drugs
Diseases
GWAS			Adiponectin levels ( 20011104 22479202 31178129) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Alanine aminotransferase levels ( 33547301) Alcohol dependence (age at onset) ( 24962325) Alcoholic chronic pancreatitis ( 28754779) Apolipoprotein A1 levels ( 32203549) Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Body mass index and HDL-C (pairwise) ( 33619380) Body mass index and type 2 diabetes (pairwise) ( 33619380) Body shape index ( 34021172) Brown vs. black hair color ( 30531825) Circulating leptin levels or type 2 diabetes ( 32341051) Coffee consumption ( 31046077) Coronary artery disease ( 29212778) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting insulin ( 33402679 34059833) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glycine levels ( 30837465) HDL cholesterol ( 24097068 30275531 20686565) HDL cholesterol levels ( 32203549 28334899) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Lung function (FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels ( 31628463) Monobrow ( 27182965) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Refractive error ( 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Rheumatoid arthritis ( 23918589) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure ( 27841878) Systolic blood pressure (dietary potassium intake interaction) ( 29212900) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Type 2 diabetes ( 24509480 30054458 29358691 30297969 30718926 28869590) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Urinary magnesium excretion ( 31993563) Urinary magnesium-to-creatinine ratio ( 29093028) Waist circumference adjusted for body mass index ( 34021172 25673412) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		38 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 DRC3 EBP EIF6 EVI2B FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MFSD14B MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 STOM SYT2 TMEM154 TMX2 TP53I3 USP13	14 interacting genes: B4GALT3 CCDC90B CRMP1 FUNDC2 GAPDH GRIPAP1 MEOX2 PDE6D PTN RPL8 TFG TUBB2A UBR1 UNC119
Entrez ID		65991	54622
HPRD ID		06586	12471
Ensembl ID		ENSG00000165775	ENSG00000185305
Uniprot IDs		Q9BWH2	Q9NXU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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