FUNDC2 and FGF14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FUNDC2	FGF14
Description		FUN14 domain containing 2	fibroblast growth factor 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity
	Biological Process	Autophagy Of Mitochondrion	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity
Pathways			Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS			Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		38 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 DRC3 EBP EIF6 EVI2B FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MFSD14B MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 STOM SYT2 TMEM154 TMX2 TP53I3 USP13	13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA
Entrez ID		65991	2259
HPRD ID		06586	03305
Ensembl ID		ENSG00000165775	ENSG00000102466
Uniprot IDs		Q9BWH2	Q92915
PDB IDs
Enriched GO Terms of Interacting Partners?
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