SMARCB1 and RINT1

Number of citations of the paper that reports this interaction (PubMedID 27229929)
8

Data Source:
BioGRID (two hybrid)

		SMARCB1	RINT1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	RAD50 interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Fibrillar Center XY Body Nucleus Nucleoplasm Nucleolus SWI/SNF Complex Protein-containing Complex Brahma Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Dsl1/NZR Complex
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding P53 Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Tat Protein Binding Nucleosomal DNA Binding	Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Blastocyst Hatching Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cell Cycle Nervous System Development Negative Regulation Of Cell Population Proliferation DNA Integration Cell Differentiation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Histone H4-K16 Acetylation	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Mitotic G2 DNA Damage Checkpoint Signaling Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Dilated cardiomyopathy ( 33677556) Dilated cardiomyopathy (MTAG) ( 33495596) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fractional shortening ( 29403010) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricle wall thickness ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular global radial strain ( 33495596) Left ventricular mass to end-diastolic volume ratio ( 33495596) N-glycan levels ( 31163085)
Interacting Genes		114 interacting genes: ABI2 AKT1 APP ARL11 ATP5F1A BCL2L11 BHLHE40 BLZF1 CALR CAMK2D CCDC120 CCDC33 CD69 CDC23 CDX2 CEBPB CHFR CNTNAP3 CXCL11 CYB5D2 DNAJA3 DPH6 FAM90A1 FAM9B FUS GADD45G GATA1 GFAP GOLGA2 HGS HNRNPM HOMEZ HOOK2 HSF2BP HSFY1 IHO1 IKZF3 IL16 KCTD9 KLC3 KLF1 KMT2B KMT2C KPNA6 KRT15 KRT19 KRT6A KRT6B KRT6C LDOC1 LENG8 LNX2 LY96 LZTS2 MAP1LC3B MAP3K20 MAPK8IP2 MBIP MCPH1 MECP2 MESD MIF4GD MRPL53 MXI1 MYC MYO18B NCK2 NONO NR0B2 NR3C1 OSGIN1 OTX2 PDPK1 PICK1 PPP1CC PPP1R15A PRKAB2 PRMT5 PSMB1 RAN RB1 RELB RINT1 RPN1 RPS6KA5 RUSC1 RXRA SAXO1 SIN3B SMARCA4 SMARCD1 SRC TACC2 TAF1D TASOR2 TEKT5 TFIP11 TLE5 TNFAIP1 TNRC6A TP53 TRIM14 TRIM27 TRIM35 TSC22D4 UBQLN4 VIM VPREB3 XPO1 YEATS4 ZC3H11A ZDHHC17 ZNF398 ZNF688	102 interacting genes: ANKRD11 ARHGAP45 ARNT2 BFSP2 BLOC1S6 BNIP3L C19orf25 C19orf44 C1orf109 C1orf35 CCDC120 CCDC121 CCDC146 CCDC187 CCDC57 CCDC88B CCHCR1 CDR2L CEP57L1 CSPP1 CWF19L2 DCTN2 DCX DPF2 EPC1 ESRRG EXOC8 FAM107A FAM110A FAM124B FAM161A FAM161B FAM81B FAM90A1 FANCG FCHSD2 GAS8 GFI1B GRAP2 HDAC4 HGS INPP5J JMY KIAA1217 KRT1 LMO2 LSP1P3 LYSMD1 MBD3 MCM7 MISP MYOZ3 NAB2 NFIL3 PCM1 PIK3R2 PIMREG PRPF18 PRPF31 PSTPIP1 RAD50 RAMAC RB1 RBL1 RBL2 RBM41 RIBC1 RNF39 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN SUOX TACO1 TEX9 TRIM69 TSEN54 TSHZ2 TSHZ3 TXLNA USHBP1 UTP14C VAV3 VPS37C XPNPEP1 ZBTB16 ZC2HC1C ZNF648 ZNF655 ZNF688 ZNF697 ZNF835 ZSCAN5B ZW10
Entrez ID		6598	60561
HPRD ID		03364	15250
Ensembl ID		ENSG00000099956	ENSG00000135249
Uniprot IDs		G5E975 Q12824 Q9H836	Q6NUQ1
PDB IDs		5AJ1 5GJK 5L7A 5L7B 6AX5 6KAG 6KZ7 6LTH 6LTJ 6UCH
Enriched GO Terms of Interacting Partners?
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