RINT1 and STRN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RINT1	STRN
Description		RAD50 interactor 1	striatin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Dsl1/NZR Complex	Cytosol Bicellular Tight Junction Postsynaptic Density Membrane Dendrite Neuronal Cell Body Dendritic Spine Postsynaptic Membrane FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding Estrogen Receptor Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Mitotic G2 DNA Damage Checkpoint Signaling Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport	Locomotory Behavior Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Dendrite Development Bicellular Tight Junction Assembly
Pathways		COPI-dependent Golgi-to-ER retrograde traffic	PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Extra-nuclear estrogen signaling Signaling by cytosolic PDGFRA and PDGFRB fusion proteins ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Alanine transaminase levels ( 29403010) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline (age-related) ( 28078323) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) High light scatter reticulocyte percentage of red cells ( 27863252) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Immature fraction of reticulocytes ( 27863252) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) PR interval ( 32439900) QRS duration ( 27577874 27659466) Red cell distribution width ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549 32154731)
Interacting Genes		102 interacting genes: ANKRD11 ARHGAP45 ARNT2 BFSP2 BLOC1S6 BNIP3L C19orf25 C19orf44 C1orf109 C1orf35 CCDC120 CCDC121 CCDC146 CCDC187 CCDC57 CCDC88B CCHCR1 CDR2L CEP57L1 CSPP1 CWF19L2 DCTN2 DCX DPF2 EPC1 ESRRG EXOC8 FAM107A FAM110A FAM124B FAM161A FAM161B FAM81B FAM90A1 FANCG FCHSD2 GAS8 GFI1B GRAP2 HDAC4 HGS INPP5J JMY KIAA1217 KRT1 LMO2 LSP1P3 LYSMD1 MBD3 MCM7 MISP MYOZ3 NAB2 NFIL3 PCM1 PIK3R2 PIMREG PRPF18 PRPF31 PSTPIP1 RAD50 RAMAC RB1 RBL1 RBL2 RBM41 RIBC1 RNF39 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN SUOX TACO1 TEX9 TRIM69 TSEN54 TSHZ2 TSHZ3 TXLNA USHBP1 UTP14C VAV3 VPS37C XPNPEP1 ZBTB16 ZC2HC1C ZNF648 ZNF655 ZNF688 ZNF697 ZNF835 ZSCAN5B ZW10	12 interacting genes: ATF7IP CALM1 CAV1 ESR1 GNAI1 LNX1 PDCD10 PPP2CA PPP2R1A PPP2R1B RINT1 TFIP11
Entrez ID		60561	6801
HPRD ID		15250	18124
Ensembl ID		ENSG00000135249	ENSG00000115808
Uniprot IDs		Q6NUQ1	O43815
PDB IDs
Enriched GO Terms of Interacting Partners?
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