FBXL17 and KBTBD8

Number of citations of the paper that reports this interaction (PubMedID 30190310)
17

Data Source:
BioGRID (affinity chromatography technology, pull down)

		FBXL17	KBTBD8
Description		F-box and leucine rich repeat protein 17	kelch repeat and BTB domain containing 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Golgi Apparatus Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Nervous System Development Regulation Of Smoothened Signaling Pathway Neural Crest Cell Differentiation Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle	Regulation Of Translation Protein Monoubiquitination Neural Crest Formation Neural Crest Cell Development
Pathways		Regulation of BACH1 activity	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Carotid intima media thickness x smoking interaction ( 32117412) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31015462) Experiencing mood swings ( 29500382) Eye color ( 23118974) General factor of neuroticism ( 30867560) Hand grip strength ( 29691431) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29235454) Irritable mood ( 29500382) Mean corpuscular volume ( 32888494) Metabolite levels ( 23823483) Moderate-to-late spontaneous preterm birth ( 31194736) Neurociticism ( 29500382) Number of children ever born ( 27798627) Pulse pressure ( 30224653) Response to amphetamines ( 22952603) smoking initiation in schizophrenia ( 33691233) Smoking status (ever vs never smokers) ( 30643258) Weight ( 28552196)	Alzheimer's disease ( 30636644) Blood urea nitrogen levels ( 29403010) Intraocular pressure ( 29617998 29785010 31959993) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Retinal detachment or retinal break ( 31816047) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Type 2 diabetes ( 25760438) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		39 interacting genes: ACSBG2 AK9 C21orf91 CCSER1 CFAP58 CLPX COG2 ETFA FILIP1L HADH IDO1 IFT46 KBTBD8 KEAP1 KLHL12 KLHL7 MED14 METAP2 OLR1 PCCB PHF7 PPP3CB PRMT1 PSME4 PXYLP1 RLF SCG5 SCPEP1 SRBD1 SUFU TASP1 TGFBI TMEM126A TMOD1 TPP2 UAP1 USP25 ZMYM2 ZNF350	2 interacting genes: FBXL17 NOLC1
Entrez ID		64839	84541
HPRD ID		10950	18138
Ensembl ID		ENSG00000145743	ENSG00000163376
Uniprot IDs		Q9UF56	Q8NFY9
PDB IDs		6W66 6WCQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?