FBXL17 and UAP1

Number of citations of the paper that reports this interaction (PubMedID 31560077)
2

Data Source:
BioGRID (pull down)

		FBXL17	UAP1
Description		F-box and leucine rich repeat protein 17	UDP-N-acetylglucosamine pyrophosphorylase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding	UDP-N-acetylglucosamine Diphosphorylase Activity Carbohydrate Binding Identical Protein Binding UDP-N-acetylgalactosamine Diphosphorylase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Nervous System Development Regulation Of Smoothened Signaling Pathway Neural Crest Cell Differentiation Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle	UDP-N-acetylglucosamine Biosynthetic Process
Pathways		Regulation of BACH1 activity	Synthesis of UDP-N-acetyl-glucosamine
Drugs			Uridine-Diphosphate-N-Acetylgalactosamine Uridine-Diphosphate-N-Acetylglucosamine
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Carotid intima media thickness x smoking interaction ( 32117412) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31015462) Experiencing mood swings ( 29500382) Eye color ( 23118974) General factor of neuroticism ( 30867560) Hand grip strength ( 29691431) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29235454) Irritable mood ( 29500382) Mean corpuscular volume ( 32888494) Metabolite levels ( 23823483) Moderate-to-late spontaneous preterm birth ( 31194736) Neurociticism ( 29500382) Number of children ever born ( 27798627) Pulse pressure ( 30224653) Response to amphetamines ( 22952603) smoking initiation in schizophrenia ( 33691233) Smoking status (ever vs never smokers) ( 30643258) Weight ( 28552196)
Interacting Genes		39 interacting genes: ACSBG2 AK9 C21orf91 CCSER1 CFAP58 CLPX COG2 ETFA FILIP1L HADH IDO1 IFT46 KBTBD8 KEAP1 KLHL12 KLHL7 MED14 METAP2 OLR1 PCCB PHF7 PPP3CB PRMT1 PSME4 PXYLP1 RLF SCG5 SCPEP1 SRBD1 SUFU TASP1 TGFBI TMEM126A TMOD1 TPP2 UAP1 USP25 ZMYM2 ZNF350	3 interacting genes: DEDD FBXL17 RGS4
Entrez ID		64839	6675
HPRD ID		10950	04178
Ensembl ID		ENSG00000145743	ENSG00000117143
Uniprot IDs		Q9UF56	A0A140VKC0 Q16222
PDB IDs		6W66 6WCQ	1JV1 1JV3 1JVD 1JVG
Enriched GO Terms of Interacting Partners?
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