GMCL1 and PAX4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GMCL1	PAX4
Description		germ cell-less 1, spermatogenesis associated	paired box 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Chromatin Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Germ Cell Development Spermatogenesis	Regulation Of Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation Pancreas Development Anatomical Structure Development
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)	Fruit consumption ( 32066663) Left-handedness ( 32989287) Metabolite levels ( 23823483) Nonsyndromic cleft palate ( 31609978) Type 2 diabetes ( 32794382 29632382 26818947 32499647 22158537 30718926 23532257) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		100 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL C5orf60 CCDC13 CCDC25 CDC37 CFAP410 CHIC2 CIB3 CLK2 CUL3 CYP26B1 EHHADH ELOA EMD EXOC3 FAM167A FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 XAGE3 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250	14 interacting genes: AURKA CABP5 EIF4A3 FBXO2 GMCL1 NAIF1 NECAB1 NFYC NME7 NRXN3 NTM NUTF2 PSMC1 UBL5
Entrez ID		64395	5078
HPRD ID		13587	01333
Ensembl ID		ENSG00000087338	ENSG00000106331
Uniprot IDs		Q53SE7 Q96IK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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