GREM2 and QSOX1

		GREM2	QSOX1
Description		gremlin 2, DAN family BMP antagonist	quiescin sulfhydryl oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Cytokine Activity Heparin Binding BMP Binding Receptor Ligand Activity	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding
	Biological Process	Animal Organ Morphogenesis Embryonic Body Morphogenesis Cytokine-mediated Signaling Pathway Sequestering Of BMP From Receptor Via BMP Binding Regulation Of Cytokine Activity	Protein Folding Negative Regulation Of Macroautophagy Extracellular Matrix Assembly
Pathways		Signaling by BMP	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Ankle-brachial index ( 22199011) Heel bone mineral density ( 31453325) Heel bone mineral density variance ( 31453325) Immune response to smallpox vaccine (IL-6) ( 22542470) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Mean corpuscular hemoglobin ( 32888494) Response to allopurinol in gout (change in serum uric acid levels) ( 30924126)	Anorexia nervosa ( 23568457) Blood protein levels ( 29875488) Pulse pressure ( 30224653 30578418)
Interacting Genes		3 interacting genes: BMP2 BMP4 QSOX1	16 interacting genes: AKIP1 BEGAIN CCR1 CCR6 CHRM4 CREG1 GPR52 GREM2 KIF5B PHAF1 PRRX1 SERPINC1 SHANK3 TNR UBE2D2 UBQLN4
Entrez ID		64388	5768
HPRD ID		16390	06785
Ensembl ID		ENSG00000180875	ENSG00000116260
Uniprot IDs		Q9H772	A0A140VKE5 O00391 Q13876
PDB IDs			3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?
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