QSOX1 and CCR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		QSOX1	CCR1
Description		quiescin sulfhydryl oxidase 1	C-C motif chemokine receptor 1
Image
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding	Phosphatidylinositol Phospholipase C Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding Chemokine (C-C Motif) Ligand 7 Binding Chemokine (C-C Motif) Ligand 5 Binding
	Biological Process	Protein Folding Negative Regulation Of Macroautophagy Extracellular Matrix Assembly	Dendritic Cell Chemotaxis Calcium Ion Transport Cellular Calcium Ion Homeostasis Exocytosis Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Response To Wounding Negative Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Calcium-mediated Signaling Positive Regulation Of Cell Migration Negative Regulation Of Bone Mineralization Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Calcium Ion Transport Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Blood protein levels ( 29875488) Pulse pressure ( 30224653 30578418)	Arthritis (juvenile idiopathic) ( 33106285) Aspartate aminotransferase levels ( 33547301) Behcet's disease ( 23291587) Celiac disease ( 22057235 20190752 30572963 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 26192919) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Myocardial infarction ( 33532862) Narcolepsy with cataplexy ( 25986216) Ulcerative colitis ( 26192919 28067908)
Interacting Genes		16 interacting genes: AKIP1 BEGAIN CCR1 CCR6 CHRM4 CREG1 GPR52 GREM2 KIF5B PHAF1 PRRX1 SERPINC1 SHANK3 TNR UBE2D2 UBQLN4	43 interacting genes: A4GNT CCL13 CCL14 CCL15 CCL16 CCL2 CCL23 CCL26 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CD74 CDC25A CREB3 CTNNB1 DAG1 DDX3Y DNAJB12 DUSP7 FAN1 GNA14 GNAI2 GRAMD1A HAS3 JAK1 KRT6A LETMD1 MBP NPM1 PLP2 PRNP PRSS50 PXMP2 QSOX1 STAT1 STAT3 TMEFF1 TMX1 TPST1 TPST2
Entrez ID		5768	1230
HPRD ID		06785	03101
Ensembl ID		ENSG00000116260	ENSG00000163823
Uniprot IDs		A0A140VKE5 O00391 Q13876	P32246 Q5U003
PDB IDs		3LLI 3LLK 3Q6O 4IJ3	1Y5D
Enriched GO Terms of Interacting Partners?
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