PJA1 and ATXN3L

Number of citations of the paper that reports this interaction (PubMedID 22626734)
6

Data Source:
BioGRID (enzymatic study)

		PJA1	ATXN3L
Description		praja ring finger ubiquitin ligase 1	ataxin 3 like
Image
GO Annotations	Cellular Component	Cytoplasm	Nucleus Mitochondrial Matrix Cytosol Mitochondrial Membrane Nuclear Inclusion Body
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Histone Deacetylase Activity Thiol-dependent Deubiquitinase Ubiquitin Protein Ligase Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Regulation Of Cell-substrate Adhesion Protein Deubiquitination Cellular Response To Heat Monoubiquitinated Protein Deubiquitination Exploration Behavior Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Histone H3 Deacetylation Cellular Response To Misfolded Protein
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Josephin domain DUBs
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Bipolar disorder ( 31043756)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3 GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	8 interacting genes: KLF5 PJA1 RFFL TRIM54 TRIM55 TRIM63 UBC USP28
Entrez ID		64219	92552
HPRD ID		02335	19697
Ensembl ID		ENSG00000181191	ENSG00000123594
Uniprot IDs		Q8NG27	B4DYC7 Q9H3M9
PDB IDs		2L0B	3O65
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?