GPSM3 and PRR5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPSM3	PRR5
Description		G protein signaling modulator 3	proline rich 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Plasma Membrane	Cytosol TORC2 Complex
	Molecular Function	Molecular_function Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Biological_process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Positive Regulation Of Protein Phosphorylation Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling TORC2 Signaling
Pathways		G alpha (i) signalling events	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases
GWAS		Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Body mass index ( 31453325) Body mass index variance ( 31453325) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)
Interacting Genes		45 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C10orf82 C11orf45 C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 YWHAZ ZNF20 ZNF581	8 interacting genes: CTNNA3 DESI1 GPSM3 HGS SCUBE1 TTC38 USHBP1 WNT7B
Entrez ID		63940	55615
HPRD ID		13605	18696
Ensembl ID		ENSG00000213654	ENSG00000186654
Uniprot IDs		A0A024RCP6 Q9Y4H4	A0A024R4U5 A8K699 P85299
PDB IDs
Enriched GO Terms of Interacting Partners?
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