BIK and TMEM199

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BIK	TMEM199
Description		BCL2 interacting killer	transmembrane protein 199
Image			No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria	Cellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Osteoprotegerin levels ( 25080503) Triglyceride levels ( 32203549)
Interacting Genes		94 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBIAD1 VAMP3 VAMP5 ZFPL1	17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B
Entrez ID		638	147007
HPRD ID		04547	12679
Ensembl ID		ENSG00000100290	ENSG00000244045
Uniprot IDs		A0A024R4X6 Q13323	Q8N511
PDB IDs		2IPE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?