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CCL25 and CCL5
Number of citations of the paper that reports this interaction (PubMedID
28381538
)
37
Data Source:
BioGRID
(pull down)
CCL25
CCL5
Description
C-C motif chemokine ligand 25
C-C motif chemokine ligand 5
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Region
Extracellular Space
Molecular Function
Hormone Activity
Protein Binding
Chemokine Activity
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Phosphatidylinositol Phospholipase C Activity
Protein Kinase Activity
Protein Binding
Chemokine Activity
Phospholipase Activator Activity
Receptor Signaling Protein Tyrosine Kinase Activator Activity
CCR1 Chemokine Receptor Binding
CCR4 Chemokine Receptor Binding
CCR5 Chemokine Receptor Binding
Chemoattractant Activity
Chemokine Receptor Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Self-association
Chemokine Receptor Antagonist Activity
CCR Chemokine Receptor Binding
Biological Process
Positive Regulation Of Cell-matrix Adhesion
Monocyte Chemotaxis
Chemotaxis
Inflammatory Response
Immune Response
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Neutrophil Chemotaxis
Positive Regulation Of GTPase Activity
Lymphocyte Chemotaxis
Cell Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Negative Regulation Of Leukocyte Tethering Or Rolling
MAPK Cascade
Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Regulation Of Chronic Inflammatory Response
Protein Phosphorylation
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Exocytosis
Chemotaxis
Inflammatory Response
Leukocyte Cell-cell Adhesion
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Response To Toxic Substance
Positive Regulation Of Activation Of Janus Kinase Activity
Positive Regulation Of Macrophage Chemotaxis
Positive Regulation Of T Cell Chemotaxis
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Smooth Muscle Cell Migration
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Cellular Biosynthetic Process
Activation Of Phospholipase D Activity
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Cell-cell Adhesion Mediated By Integrin
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of T Cell Proliferation
Neutrophil Activation
Positive Regulation Of Phosphorylation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Protein Kinase B Signaling
Positive Regulation Of GTPase Activity
Negative Regulation By Host Of Viral Transcription
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Positive Regulation Of Innate Immune Response
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Translational Initiation
Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
Eosinophil Chemotaxis
Macrophage Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Insulin Secretion
Regulation Of T Cell Activation
Positive Chemotaxis
Positive Regulation Of Calcium Ion Transport
Positive Regulation Of Protein Tyrosine Kinase Activity
Chemokine-mediated Signaling Pathway
Negative Regulation Of Chemokine-mediated Signaling Pathway
Negative Regulation Of T Cell Apoptotic Process
Positive Regulation Of T Cell Apoptotic Process
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Monocyte Chemotaxis
Cellular Response To Virus
Regulation Of Neuron Death
Positive Regulation Of T Cell Migration
Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Drugs
Heparin Disaccharide I-S
Heparin Disaccharide Iii-S
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Metabolite levels (
23823483
)
Neurocognitive impairment in HIV-1 infection (continuous) (
28447399
)
Sphingolipid levels (
26068415
)
Blood protein levels (
30072576
28240269
)
Interacting Genes
12 interacting genes:
ACKR2
ACKR4
CCL17
CCL5
CCR10
CCR9
CXCL11
CXCL12
CXCL17
PF4
PF4V1
SMARCA4
56 interacting genes:
AATF
ACKR1
ACKR2
ACKR4
APC
BAG4
BCAR3
CCL11
CCL13
CCL16
CCL17
CCL2
CCL20
CCL21
CCL24
CCL25
CCL26
CCL27
CCL28
CCR1
CCR3
CCR4
CCR5
CHEK2
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL6
CXCL8
CXCL9
DPP4
EDC4
FZR1
GRB2
IGFBP7
KRAS
PALB2
PF4
PHB
PIGR
PPBP
PTPN1
RANGAP1
RELA
SDC1
SDC4
SLC2A5
TGFB1
TRIP6
VCAN
WT1
XCL1
XCL2
Entrez ID
6370
6352
HPRD ID
03976
01751
Ensembl ID
ENSG00000131142
ENSG00000271503
Uniprot IDs
O15444
A0A494C1Q1
D0EI67
P13501
PDB IDs
1B3A
1EQT
1HRJ
1RTN
1RTO
1U4L
1U4M
1U4P
1U4R
2L9H
2VXW
5CMD
5COY
5DNF
5L2U
5UIW
6AEZ
6C6D
6FGP
6LOG
6STK
Enriched GO Terms of Interacting Partners
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