CCL25 and CCR10

Number of citations of the paper that reports this interaction (PubMedID 10706668)
44

Data Source:
HPRD (in vitro)

		CCL25	CCR10
Description		C-C motif chemokine ligand 25	C-C motif chemokine receptor 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Negative Regulation Of Leukocyte Tethering Or Rolling	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Sphingolipid levels ( 26068415)
Interacting Genes		12 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1 SMARCA4	11 interacting genes: ARPC3 CCL19 CCL2 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A RAB5C
Entrez ID		6370	2826
HPRD ID		03976	02586
Ensembl ID		ENSG00000131142	ENSG00000184451
Uniprot IDs		O15444	P46092
PDB IDs
Enriched GO Terms of Interacting Partners?
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