ATXN7 and MPRIP

Number of citations of the paper that reports this interaction (PubMedID 21078624)
26

Data Source:
BioGRID (two hybrid)

		ATXN7	MPRIP
Description		ataxin 7	myosin phosphatase Rho interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Microtubule Cytoskeleton Nuclear Matrix	Cytosol Focal Adhesion Actin Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Microtubule Cytoskeleton Organization Nucleus Organization Negative Regulation Of Microtubule Depolymerization Visual Perception Histone Deubiquitination	Actin Filament Organization
Pathways		HATs acetylate histones Ub-specific processing proteases	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Cortical surface area (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 31152163) Red cell distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 30054458)	Diabetic retinopathy ( 21441570) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Hemoglobin ( 32888494) Obesity-related traits ( 23251661)
Interacting Genes		65 interacting genes: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CPOX CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GNAT1 GOLGA2 GOLGA3 GPRASP1 GRN IMPDH2 ITPRID2 JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PDHB PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SERINC3 SIAH1 SNX1 SPRY1 SUMO1 SUMO2 SYNJ2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 USP22 VCP VWF	16 interacting genes: ATXN7 COL6A1 IKBKG LSM8 NOS3 PIAS4 PPP1R12A PPP1R12C PTEN RACGAP1 RHOA SMARCA2 YTHDC1 YWHAB YWHAG YWHAQ
Entrez ID		6314	23164
HPRD ID		06365	17591
Ensembl ID		ENSG00000163635	ENSG00000133030
Uniprot IDs		O15265 Q9UPD8	Q6WCQ1 Q8N236
PDB IDs		2KKR
Enriched GO Terms of Interacting Partners?
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