SAT1 and RPP25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SAT1	RPP25
Description		spermidine/spermine N1-acetyltransferase 1	ribonuclease P and MRP subunit p25
Image
GO Annotations	Cellular Component	Cytosol	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Interconversion of polyamines	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Myocardial infarction ( 33532862) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TEAD4 TEX43 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438
Entrez ID		6303	54913
HPRD ID		02431	15276
Ensembl ID		ENSG00000130066	ENSG00000178718
Uniprot IDs		A0A384NQ10 P21673	Q9BUL9
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	6AHR 6AHU 6CWX 6LT7
Enriched GO Terms of Interacting Partners?
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