SAT1 and HSPE1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		SAT1	HSPE1
Description		spermidine/spermine N1-acetyltransferase 1	heat shock protein family E (Hsp10) member 1
Image
GO Annotations	Cellular Component	Cytosol	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways		Interconversion of polyamines	RHOG GTPase cycle
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine	Phenethyl Isothiocyanate
Diseases
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TEAD4 TEX43 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	16 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 NTAQ1 SAT1 SELENOM STK3 TLE1 UNC119 ZHX1
Entrez ID		6303	3336
HPRD ID		02431	02535
Ensembl ID		ENSG00000130066	ENSG00000115541
Uniprot IDs		A0A384NQ10 P21673	A0A384N6A4 P61604
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	4PJ1 6HT7 6MRC 6MRD
Enriched GO Terms of Interacting Partners?
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