S100A13 and IL1A

Number of citations of the paper that reports this interaction (PubMedID 12746488)
26

Data Source:
HPRD (in vitro)

		S100A13	IL1A
Description		S100 calcium binding protein A13	interleukin 1 alpha
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Cytosol
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding RAGE Receptor Binding	Cytokine Activity Interleukin-1 Receptor Binding Copper Ion Binding Protein Binding
	Biological Process	Positive Regulation Of Cytokine Production Positive Regulation Of Cell Population Proliferation Protein Transport Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Degranulation	Fever Generation Positive Regulation Of Cytokine Production Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Cellular Sodium Ion Homeostasis Apoptotic Process Inflammatory Response Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Immature T Cell Proliferation In Thymus Cellular Response To Heat Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Angiogenesis Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Response To Copper Ion Positive Regulation Of Protein Secretion Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cell Division Cellular Response To Lipopolysaccharide Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Senescence-Associated Secretory Phenotype (SASP) Interleukin-1 processing Pyroptosis Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling Interleukin-1 signaling Purinergic signaling in leishmaniasis infection
Drugs		Olopatadine Amlexanox Calcium chloride Calcium Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	Rilonacept
Diseases
GWAS		Plateletcrit ( 32888494)	Dysmenorrheic pain severity ( 29855537) Endometriosis ( 20844546 28537267) Gestational age at birth (child effect) ( 31477735) Interleukin-1-receptor antagonist levels ( 22205395) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post-term birth ( 31477735) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes		9 interacting genes: FBXO7 FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 S100A14 SYT1	11 interacting genes: CAPN1 CASP1 HAX1 IL1R1 IL1R2 IL1RAP KPNA6 MEOX2 NDN NFKBIE S100A13
Entrez ID		6284	3552
HPRD ID		03586	00988
Ensembl ID		ENSG00000189171	ENSG00000115008
Uniprot IDs		Q99584	P01583
PDB IDs		1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9	1ITA 2ILA 2KKI 2L5X 5UC6
Enriched GO Terms of Interacting Partners?
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