S100A4 and FCGR3A

Number of citations of the paper that reports this interaction (PubMedID 23024279)
8

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		S100A4	FCGR3A
Description		S100 calcium binding protein A4	Fc fragment of IgG receptor IIIa
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Transmembrane Signaling Receptor Activity IgG Binding
	Biological Process	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Immune Response Cell Surface Receptor Signaling Pathway Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs		Trifluoperazine Copper	Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Alefacept Palivizumab Daclizumab Bevacizumab Catumaxomab Sarilumab Benralizumab
Diseases
GWAS		Blood protein levels ( 29875488) Pulse pressure ( 30578418)	Alanine aminotransferase levels ( 33547301) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Birth weight ( 31043758) Blood protein levels ( 28240269) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Hemoglobin ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Monocyte percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 28714469) Takayasu arteritis ( 30498034 23830517) Type 1 diabetes (age at diagnosis) ( 33179336) Ulcerative colitis ( 28067908)
Interacting Genes		28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119	20 interacting genes: APCS APP CD247 CD38 CD4 FCER1G FCGR1A FCGR2A GP6 IGHG1 LCK LXN PRKCA PRKCI PTPRC S100A4 SHC1 SYK ZAP70 ZBTB25
Entrez ID		6275	2214
HPRD ID		15914	00903
Ensembl ID		ENSG00000196154	ENSG00000203747
Uniprot IDs		P26447	H0Y755 P08637
PDB IDs		1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58	3AY4 3SGJ 3SGK 3WN5 5BW7 5D6D 5ML9 5MN2 5VU0 5XJE 5XJF 5YC5
Enriched GO Terms of Interacting Partners?
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