RRAD and NME1

Number of citations of the paper that reports this interaction (PubMedID 10611312)
31

Data Source:
HPRD (in vitro, in vivo)

		RRAD	NME1
Description		RRAD, Ras related glycolysis inhibitor and calcium channel regulator	NME/NM23 nucleoside diphosphate kinase 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Cytoplasm Mitochondrial Outer Membrane Centrosome Cytosol Intermediate Filament Membrane Ruffle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding	Magnesium Ion Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding RNA Binding Deoxyribonuclease Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding GTP Binding Intermediate Filament Binding Enzyme Binding Identical Protein Binding Gamma-tubulin Binding Ribosomal Small Subunit Binding
	Biological Process	Small GTPase Mediated Signal Transduction Negative Regulation Of High Voltage-gated Calcium Channel Activity	Negative Regulation Of Myeloid Leukocyte Differentiation Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Metabolic Process Endocytosis Lactation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Response To Amine Hippocampus Development Cell Differentiation Response To Testosterone Regulation Of Apoptotic Process Positive Regulation Of DNA Binding Positive Regulation Of Epithelial Cell Proliferation Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Fatty Acid Cellular Response To Xenobiotic Stimulus
Pathways		NGF-stimulated transcription	Interconversion of nucleotide di- and triphosphates
Drugs			Zinc 2'-Deoxyguanosine-5'-Triphosphate Selenocysteine 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate Adenosine Phosphonoacetic Acid Stavudine triphosphate Thymidine-5'- Diphosphate 2'-Deoxyguanosine-5'-Diphosphate 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate Guanosine-5'-Diphosphate 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate Zidovudine diphosphate Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Waist circumference adjusted for body mass index ( 34021172)	Bipolar disorder ( 31043756) Conjunctival UV autofluorescence (CUVAF) ( 25590795) Metabolite levels ( 23823483)
Interacting Genes		15 interacting genes: CALM1 CAMK2G CCDC141 CSNK2A1 CSNK2B EEA1 EGFR MMP14 NME1 PRKACA PRKCA PRKCB STAT3 TPM2 YWHAZ	32 interacting genes: APEX1 AURKA CCND3 FBXO24 FXR1 FXR2 GORASP2 ITGB1 KSR1 LNX1 MIF NIF3L1 NME2 NME3 NME4 NTAQ1 NUTF2 PID1 POLR1C PRUNE1 RAC1 RORA RORB RRAD SET SMARCD1 SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 TNPO3
Entrez ID		6236	4830
HPRD ID		01536	01131
Ensembl ID		ENSG00000166592	ENSG00000239672
Uniprot IDs		A0A024R6X0 P55042	A0A384MTW7 P15531
PDB IDs		2DPX 2GJS 3Q72 3Q7P 3Q7Q	1JXV 1UCN 2HVD 2HVE 3L7U 4ENO 5UI4
Enriched GO Terms of Interacting Partners?
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