RPN1 and ADRM1

Number of citations of the paper that reports this interaction (PubMedID 16990800)
122

Data Source:
HPRD (in vitro)

		RPN1	ADRM1
Description		ribophorin I	ADRM1 26S proteasome ubiquitin receptor
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Melanosome	Proteasome Complex Nucleoplasm Cytosol Plasma Membrane Proteasome Regulatory Particle, Lid Subcomplex
	Molecular Function	RNA Binding Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding	Protease Binding Protein Binding Ubiquitin Binding Endopeptidase Activator Activity Proteasome Binding
	Biological Process	Cellular Protein Modification Process Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine	Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Endopeptidase Activity Proteasome Assembly
Pathways		SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein	UCH proteinases Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil counts ( 29403010 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mild to moderate chronic kidney disease ( 31178898) Monocyte count ( 23314186 29403010 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil count ( 32888494) Platelet distribution width ( 32888494) Serum metabolite levels ( 33031748) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 32888494 21738480) White blood cell count (basophil) ( 29403010)	Prostate cancer ( 23535732)
Interacting Genes		17 interacting genes: ADRM1 DPF1 DUX4 ERBB3 HSPA5 KRTAP1-3 RAB7A RAD23A RBBP4 SGTA SIGIRR SMARCB1 UBC UBQLN1 UBQLN2 UBQLN4 WSB2	24 interacting genes: APP ATP6V0D2 CDC42 DDI1 EGFR MAILR MX1 PRKN PSMD1 PSMD14 PSMD2 PSMD4 RAD23A RAD23B RPN1 RPN2 SGTA SMURF1 STUB1 UBC UBE3A UBQLN1 UBQLN2 UCHL5
Entrez ID		6184	11047
HPRD ID		01598	06440
Ensembl ID		ENSG00000163902	ENSG00000130706
Uniprot IDs		P04843	A0A087WX59 Q16186
PDB IDs		6S7O 6S7T	2KQZ 2KR0 2L5V 2MKZ 2NBV 4UEL 4UEM 4WLQ 4WLR 5IRS 5V1Y 5V1Z 5YMY 6CO4 6OI4 6UYI 6UYJ
Enriched GO Terms of Interacting Partners?
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