RPL4 and NDRG1

Number of citations of the paper that reports this interaction (PubMedID 17220478)
24

Data Source:
HPRD (in vivo)

		RPL4	NDRG1
Description		ribosomal protein L4	N-myc downstream regulated 1
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Rough Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex	Nucleus Cytoplasm Centrosome Cytosol Microtubule Plasma Membrane Adherens Junction Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Glutamatergic Synapse
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding Microtubule Binding Small GTPase Binding Gamma-tubulin Binding Cadherin Binding
	Biological Process	Cytoplasmic Translation Translation	Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Mast Cell Activation Cellular Response To Hypoxia Postsynapse Organization
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Drugs		Artenimol
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462) Left-handedness ( 32989287) Nontyphoidal Salmonella bacteraemia ( 29523850) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes		19 interacting genes: ADD3 APBB1 APOE DUX4 DUX4L9 IL32 MAP3K14 MDM2 MYB NDRG1 OGT PBX2 PIN1 PRPF40A SORBS1 SUMO2 TLE3 TNPO2 TSC2	72 interacting genes: ACSL3 ACTG1 AP1M2 AP2M1 APOA1 APOA2 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E EWSR1 FASN GPAA1 GSK3B HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME MYC NCL NR4A1 PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RTN1 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS1 TFAP2B TLE3 UPF1 VCP XRCC5 ZNF155
Entrez ID		6124	10397
HPRD ID		01607	05586
Ensembl ID		ENSG00000174444	ENSG00000104419
Uniprot IDs		P36578	B3KWB2 Q8N959 Q92597
PDB IDs		4UG0 4V6X 5A8L 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP	6ZMM
Enriched GO Terms of Interacting Partners?
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