NUDT12

Description		nudix hydrolase 12
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GO Annotations	Cellular Component	Nucleus Cytoplasm Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	NAD+ Diphosphatase Activity Magnesium Ion Binding Protein Binding Zinc Ion Binding NADH Pyrophosphatase Activity RNA NAD-cap (NMN-forming) Hydrolase Activity Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	MRNA Catabolic Process NADH Metabolic Process NADP Catabolic Process NAD Catabolic Process Circadian Regulation Of Gene Expression NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic NAD-cap Decapping Methylguanosine-cap Decapping
Pathways		Nicotinamide salvaging
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131) Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Blood protein levels ( 29875488) Body size at age 10 ( 32376654) Depression (quantitative trait) ( 23290196) Fasting glucose change ( 31263163) Gut microbiota (functional units) ( 27694959) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Longevity ( 30294719) Mitochondrial DNA levels ( 25240745) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Response to fenofibrate (total cholesterol levels) ( 27002377) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Triglyceride levels ( 32203549)
Interacting Genes		3 interacting genes: BLMH CAMK4 RPGR
Entrez ID		83594
HPRD ID		10123
Ensembl ID		ENSG00000112874
Uniprot IDs		Q9BQG2
PDB IDs		6SCX
Enriched GO Terms of Interacting Partners?
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