RNF5 and PRAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RNF5	PRAF2
Description		ring finger protein 5	PRA1 domain family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment	Endosome Membrane Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Response To Bacterium Negative Regulation Of Autophagy Ubiquitin-dependent ERAD Pathway Protein Destabilization ERAD Pathway Cellular Protein Catabolic Process Transmembrane Transport Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination ER-associated Misfolded Protein Catabolic Process Endoplasmic Reticulum Mannose Trimming Regulation Of Autophagosome Assembly	Protein Transport L-glutamate Transmembrane Transport
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Advanced glycation end-product levels ( 26083729) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		50 interacting genes: ABHD16A ARL6IP1 CFTR CYB561 CYB561A3 DGAT2L6 FAM241B FHOD1 GLP1R INSIG2 JKAMP LEPROTL1 MAVS MPDZ MS4A1 ORMDL3 PLP2 PLPP6 PRAF2 PXN RABAC1 RHBDD1 RUSF1 SCD SEC22A SLC1A1 SLC38A7 TGFBR1 TMEM120B TMEM242 TNFAIP3 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G2 UBE2K UBE2N UBE2U UBE2V1 UBE2W UBE2Z UBTD1 YIPF1 YIPF2 YIPF4	26 interacting genes: ABHD16A ADGRD1 AGR3 AQP6 ARL6IP5 CCR5 CD79A CIAO2A CLEC10A EBAG9 GJA5 GJA8 GPR152 HIBADH HSD17B11 MCEMP1 MIEF1 NDRG4 REEP4 RETREG3 RNF5 SLC10A6 TLCD4 TMEM14B TMX2 ZDHHC15
Entrez ID		6048	11230
HPRD ID		04057	06596
Ensembl ID		ENSG00000204308	ENSG00000243279
Uniprot IDs		A0A024RCQ4 Q99942	A0A024QZ22 O60831
PDB IDs
Enriched GO Terms of Interacting Partners?
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