RFC5 and ZNF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RFC5	ZNF19
Description		replication factor C subunit 5	zinc finger protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex	Nucleus
	Molecular Function	DNA Binding DNA Clamp Loader Activity Protein Binding ATP Binding Single-stranded DNA Helicase Activity Enzyme Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	DNA Replication DNA-dependent DNA Replication DNA Repair DNA Duplex Unwinding Positive Regulation Of DNA-directed DNA Polymerase Activity	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint	Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic rhinosinusitis ( 33393196) Metabolite levels ( 23823483) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Physiological traits ( 31902109)	Blood protein levels ( 28240269) Intelligence (MTAG) ( 29326435)
Interacting Genes		36 interacting genes: ARID5A BIRC2 CCNC CHTF18 COPS6 DAPK1 DDIT4L DYNLL1 EEF1A1 EML2 EXOSC8 FAM166B KRT34 LMO3 LRIF1 MED31 N4BP3 NAB2 NR5A1 PCNA PPP1R16B PTEN RBM48 RFC2 RFC4 SUMO2 TASOR2 TRIM38 TSNAX UNC119 XAF1 XIAP YPEL3 ZMAT1 ZNF19 ZNF426	22 interacting genes: AP1M1 ATPAF2 BCCIP BEX2 CARD9 CDR2L CIB3 CINP CSNK2B CTNNA3 FAM72D HOMER3 LMO1 LMO2 MAGOHB NDUFAB1 NUDT22 RFC5 SCNM1 SPANXN2 STX11 ZNF417
Entrez ID		5985	7567
HPRD ID		02677	01914
Ensembl ID		ENSG00000111445	ENSG00000157429
Uniprot IDs		P40937 Q59GW7	P17023
PDB IDs		1LFS 6VVO
Enriched GO Terms of Interacting Partners?
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