KLHL12 and INMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KLHL12	INMT
Description		kelch like family member 12	indolethylamine N-methyltransferase
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GO Annotations	Cellular Component	Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Thioether S-methyltransferase Activity Protein Binding N-methyltransferase Activity Amine N-methyltransferase Activity S-adenosyl-L-methionine:beta-alanine N-methyltransferase Activity
	Biological Process	Protein Monoubiquitination Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating	Amine Metabolic Process Response To Toxic Substance Methylation
Pathways		Degradation of DVL	Methylation of MeSeH for excretion
Drugs
Diseases
GWAS			Glucose homeostasis traits ( 25524916) Nephrolithiasis ( 22396660) Urolithiasis ( 30975718)
Interacting Genes		62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KEAP1 KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4	2 interacting genes: KLHL12 LNX2
Entrez ID		59349	11185
HPRD ID		13925	06890
Ensembl ID		ENSG00000117153	ENSG00000241644
Uniprot IDs		Q53G59 Q9H7R2	O95050
PDB IDs		2VPJ 6TTK 6V7O	2A14
Enriched GO Terms of Interacting Partners?
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