RBBP6 and HP

Number of citations of the paper that reports this interaction (PubMedID 18624398)
18

Data Source:
BioGRID (two hybrid)

		RBBP6	HP
Description		RB binding protein 6, ubiquitin ligase	haptoglobin
Image
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Centrosome Cytosol Nuclear Speck Protein-containing Complex	Extracellular Region Extracellular Space Haptoglobin-hemoglobin Complex Specific Granule Lumen Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle Tertiary Granule Lumen
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Activity	Serine-type Endopeptidase Activity Protein Binding Antioxidant Activity Hemoglobin Binding
	Biological Process	In Utero Embryonic Development DNA Replication Regulation Of DNA Replication MRNA Processing Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Multicellular Organism Growth Embryonic Organ Development Somite Development	Acute Inflammatory Response Defense Response Acute-phase Response Positive Regulation Of Cell Death Zymogen Activation Response To Hydrogen Peroxide Defense Response To Bacterium Negative Regulation Of Oxidoreductase Activity Cellular Oxidant Detoxification Negative Regulation Of Hydrogen Peroxide Catabolic Process
Pathways		RHOBTB1 GTPase cycle Antigen processing: Ubiquitination & Proteasome degradation	Scavenging of heme from plasma Neutrophil degranulation
Drugs			Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062) Body size at age 10 ( 32376654) Brain structure ( 20171287) Chronotype ( 30696823) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Apolipoprotein A1 levels ( 33730874) Blood protein levels ( 29875488 28240269) Cholesterol, total ( 25961943 20686565) Haptoglobin levels ( 22403646) Hemoglobin levels ( 32327693) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) LDL cholesterol ( 25961943 20686565) Low density lipoprotein cholesterol levels ( 29403010) Metabolite levels ( 22916037) Metabolite levels (small molecules and protein measures) ( 27005778) Morning person ( 30696823) Parental lifespan ( 30642433) Plasma haptoglobin levels in type 2 diabetes ( 29572449) Total cholesterol levels ( 29403010 33339817) Urinary haptoglobin levels in type 2 diabetes ( 29572449)
Interacting Genes		41 interacting genes: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CASK CD81 CLK1 ETS1 EVA1C FAAP24 FBXO7 GLUL GRB2 HP IL4R KHDRBS3 LINC00305 LRCH4 MAD2L2 MDM2 MIR19A MIR19B1 NDUFB9 NEK6 PIAS1 PLG RB1 RBP4 RCC1L RPS14 SMN1 SPP1 TP53 TPT1 UBE2I UPF3B VAV2 YBX1 ZBTB38 ZFYVE9	21 interacting genes: ADAMTS4 ATP7B C1RL CD163 CD22 GADD45G GRB2 HBB HSP90AA1 ITGAM ITGB2 LAMC3 MVP RBBP6 RPL11 SMAD3 TBL1X TGM2 TP63 VKORC1 WASL
Entrez ID		5930	3240
HPRD ID		02964	00772
Ensembl ID		ENSG00000122257	ENSG00000257017
Uniprot IDs		Q7Z6E9	A0A0C4DGL8 P00738 Q6PEJ8
PDB IDs		2C7H 2YSA 2YUR 3ZTG 6E5X	4WJG 4X0L 5HU6 6TB2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?