LRRC4C and SNAP47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LRRC4C	SNAP47
Description		leucine rich repeat containing 4C	synaptosome associated protein 47
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Plasma Membrane Endomembrane System SNARE Complex Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion	Exocytosis Vesicle Fusion Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mastocytosis (KIT D816V positive) ( 33421400) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6	23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59
Entrez ID		57689	116841
HPRD ID		12303	17148
Ensembl ID		ENSG00000148948	ENSG00000143740
Uniprot IDs		Q4JIV9 Q4JIW0 Q9HCJ2	A0A087X0B7 Q5SQN1
PDB IDs		3ZYJ
Enriched GO Terms of Interacting Partners?
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