ZBTB2 and IP6K2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZBTB2	IP6K2
Description		zinc finger and BTB domain containing 2	inositol hexakisphosphate kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cell Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Inositol Heptakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Inositol Diphosphate Tetrakisphosphate Kinase Activity Flavonoid Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Phosphate Ion Transport Phosphorylation Negative Regulation Of Cell Growth Inositol Phosphate Biosynthetic Process Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Cellular Response To Flavonoid
Pathways			Synthesis of IPs in the nucleus Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Chronic myeloid leukemia ( 21540461) Monocyte count ( 32888494) Refractive error ( 32231278)	Adult body size ( 32376654) Age at first birth ( 34211149) Apolipoprotein A1 levels ( 33730874) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Morning person ( 30696823) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		29 interacting genes: ARID1B CREBBP DAXX GABARAPL2 IP6K2 KAT5 LHX4 LNX1 MEOX2 MKLN1 MOS MRPL11 PICK1 PIN1 RASSF8 SP1 STAT6 SUMO1 SUMO2 SUV39H1 TENT5B TMC6 TP53 UBE2I ZBTB18 ZBTB25 ZBTB49 ZMYND19 ZNF639	8 interacting genes: HSP90AA1 LNX2 MEOX2 PLOD3 PLSCR1 QRICH1 RBPMS ZBTB2
Entrez ID		57621	51447
HPRD ID		10314	07380
Ensembl ID		ENSG00000181472	ENSG00000068745
Uniprot IDs		Q8N680	A8K636 B2RCP4 Q9UHH9
PDB IDs
Enriched GO Terms of Interacting Partners?
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