IP6K2 and ZBTB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IP6K2	ZBTB2
Description		inositol hexakisphosphate kinase 2	zinc finger and BTB domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cell Junction	Nucleoplasm
	Molecular Function	Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Inositol Heptakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Inositol Diphosphate Tetrakisphosphate Kinase Activity Flavonoid Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Phosphate Ion Transport Phosphorylation Negative Regulation Of Cell Growth Inositol Phosphate Biosynthetic Process Positive Regulation Of Apoptotic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Cellular Response To Flavonoid	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Synthesis of IPs in the nucleus Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Apolipoprotein A1 levels ( 33730874) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Morning person ( 30696823) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist circumference adjusted for body mass index ( 34021172)	Chronic myeloid leukemia ( 21540461) Monocyte count ( 32888494) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: HSP90AA1 LNX2 MEOX2 PLOD3 PLSCR1 QRICH1 RBPMS ZBTB2	29 interacting genes: ARID1B CREBBP DAXX GABARAPL2 IP6K2 KAT5 LHX4 LNX1 MEOX2 MKLN1 MOS MRPL11 PICK1 PIN1 RASSF8 SP1 STAT6 SUMO1 SUMO2 SUV39H1 TENT5B TMC6 TP53 UBE2I ZBTB18 ZBTB25 ZBTB49 ZMYND19 ZNF639
Entrez ID		51447	57621
HPRD ID		07380	10314
Ensembl ID		ENSG00000068745	ENSG00000181472
Uniprot IDs		A8K636 B2RCP4 Q9UHH9	Q8N680
PDB IDs
Enriched GO Terms of Interacting Partners?
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