PTK7 and TPTE2

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		PTK7	TPTE2
Description		protein tyrosine kinase 7 (inactive)	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Golgi Membrane Nucleus Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Membrane Cell Projection
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Dephosphorylation Phosphatidylinositol Biosynthetic Process Negative Regulation Of Cell Population Proliferation Phosphatidylinositol 3-kinase Signaling Dephosphorylation Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation Cell Motility Regulation Of Protein Kinase B Signaling
Pathways			Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes		48 interacting genes: BYSL CDC14A CDKN1A CLIC5 CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ENPP5 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PSMB9 PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR RPS2 RTN4R STYX TNFRSF21 TPTE TPTE2 TRAM2 VGLL1	5 interacting genes: AATK BRCA1 EPHA2 LMTK2 PTK7
Entrez ID		5754	93492
HPRD ID		03534	06003
Ensembl ID		ENSG00000112655	ENSG00000132958
Uniprot IDs		Q13308	Q6XPS3
PDB IDs		6VG3
Enriched GO Terms of Interacting Partners?
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