PBXIP1 and BRPF1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PBXIP1	BRPF1
Description		PBX homeobox interacting protein 1	bromodomain and PHD finger containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytosol Microtubule Membrane	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding	DNA Binding Protein Binding Acetyltransferase Activator Activity Histone Binding Metal Ion Binding
	Biological Process	Production Of Molecular Mediator Involved In Inflammatory Response Cell Adhesion Multicellular Organism Development Cell Migration Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Articular Cartilage Development Histone H3-K56 Acetylation Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity	Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		28 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TRAF7 TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	11 interacting genes: CDCA7L CEP63 CEP70 GTF2H1 H3C14 KIAA0753 NECAB1 NFE2L2 PBXIP1 USHBP1 USP20
Entrez ID		57326	7862
HPRD ID		17823	03875
Ensembl ID		ENSG00000163346	ENSG00000156983
Uniprot IDs		B4E0K4 Q96AQ6	P55201
PDB IDs			2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8 4LC2 4QYD 4QYL 4UYE 5C6S 5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA 5DYC 5E3D 5E3G 5EM3 5EPR 5EPS 5EQ1 5ERC 5ETB 5ETD 5EV9 5EVA 5EWC 5EWD 5EWH 5EWV 5EWW 5FFV 5FFW 5FFY 5FG4 5FG5 5G4R 5G4S 5MWG 5MWH 5MWZ 5MYG 5O4S 5O4T 5O55 5O5A 5O5F 5O5H 5OV8 5OWA 5OWB 5OWE 5T4U 5T4V 6EKQ 6U04 7C4I
Enriched GO Terms of Interacting Partners?
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