PBXIP1 and ZZZ3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PBXIP1	ZZZ3
Description		PBX homeobox interacting protein 1	zinc finger ZZ-type containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytosol Microtubule Membrane	Nucleoplasm Nucleolus
	Molecular Function	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Production Of Molecular Mediator Involved In Inflammatory Response Cell Adhesion Multicellular Organism Development Cell Migration Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Articular Cartilage Development Histone H3-K56 Acetylation Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity	Histone H4 Acetylation
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body shape index ( 34021172) Height ( 31562340) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Obesity ( 23563607) Platelet count ( 32888494) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		28 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TRAF7 TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	21 interacting genes: BLZF1 CARD9 DNAJB11 EFHC2 EPS8 FAM124A GATA1 GOLGA2 IKBKG LZTR1 MAML3 PBXIP1 PCBD2 PICK1 PPP1R13B TRAF2 TRIM22 ZBTB9 ZNF212 ZNF496 ZNF513
Entrez ID		57326	26009
HPRD ID		17823	15907
Ensembl ID		ENSG00000163346	ENSG00000036549
Uniprot IDs		B4E0K4 Q96AQ6	Q8IYH5
PDB IDs			2FC7 2YUM 6E83 6E86
Enriched GO Terms of Interacting Partners?
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