THAP11 and HEMGN

Number of citations of the paper that reports this interaction (PubMedID 24740910)
11

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		THAP11	HEMGN
Description		THAP domain containing 11	hemogen
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Cell Differentiation Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)	Alopecia areata ( 25608926) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Quantitative traits ( 19197348) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		21 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 OGT PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	34 interacting genes: AURKA AXIN2 BCL10 BUB1 CDH1 CTBP1 CTBP2 DCC DLC1 EGFR ENO1 EP300 FBXW7 FLCN GATA1 H2AC6 HMGA1 HSPA1A KAT6A KRAS MCC MED17 MLH3 NRAS ODC1 PTPRJ SMAD4 SP100 SRC THAP11 TLR2 TRAF3 WHRN ZBTB1
Entrez ID		57215	55363
HPRD ID		11629	17100
Ensembl ID		ENSG00000168286	ENSG00000136929
Uniprot IDs		Q96EK4	A0A024R162 Q9BXL5
PDB IDs		2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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