MFF and TMX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MFF	TMX2
Description		mitochondrial fission factor	thioredoxin related transmembrane protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Integral Component Of Mitochondrial Outer Membrane Integral Component Of Mitochondrial Membrane Protein-containing Complex	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane Membrane-bounded Organelle Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Targeting To Membrane Regulation Of Peroxisome Organization	Brain Development
Pathways
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		105 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UNC50 UNC93B1 UPK1B VAMP4 ZFPL1	163 interacting genes: AGPAT3 AGPAT4 AGPAT5 AIG1 AQP6 ARV1 ASGR1 ASPH ATXN1 BDKRB1 BET1 BNIP1 BNIP2 BNIP3 BRICD5 BTN2A2 C2CD2L C3orf52 CCDC167 CCL2 CD81 CDIPT CDS2 CMTM7 COL8A2 COMMD8 COX20 CTSA CTXN3 CXCL16 CXorf66 CYBC1 CYP4F2 DERL1 DGAT2L6 EMD EMP3 F2RL1 FA2H FAM177A1 FAM241B FAM3C FAXDC2 FDFT1 FUNDC2 FXYD6-FXYD2 GIMAP1 GIMAP5 GJB2 HACD2 HHATL HMOX2 HSD17B11 HSD17B13 HTATIP2 IER3 IER3IP1 IGFBP5 INSIG2 ITGAM LEPROT LEPROTL1 LHFPL5 LRAT MALL MFF MFSD14B MGLL MGST3 MIP MLN MS4A1 MTNR1A NAT8 NDUFA3 NINJ2 NRM NSDHL NSG1 ORMDL2 OTULINL PAEP PEDS1-UBE2V1 PEX16 PKMYT1 PLP2 PNLIPRP1 PRAF2 PRB1 PTAFR PTPN9 RABAC1 REEP2 REEP4 RFT1 RNF24 RTP2 RUSF1 SACM1L SCAMP5 SCD SELENOK SERF1A SERF1B SERP2 SFT2D1 SFXN1 SFXN3 SLC22A18 SLC22A2 SLC29A2 SLC35A1 SMAGP SMCO4 SMIM1 STATH STX12 STX3 STX7 THBD THSD7B TMBIM6 TMEM115 TMEM120A TMEM120B TMEM121 TMEM128 TMEM140 TMEM14B TMEM14C TMEM176A TMEM201 TMEM203 TMEM208 TMEM222 TMEM239 TMEM254 TMEM31 TMEM50B TMEM51 TMEM65 TMEM71 TMEM86B TMEM97 TPRG1 TRAM1L1 TREX1 TSNARE1 TSPAN2 TVP23B UBE2J1 UNC93A VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB WFDC2 YIF1A YIPF1 YIPF2 YIPF6
Entrez ID		56947	51075
HPRD ID		16653	07159
Ensembl ID		ENSG00000168958	ENSG00000213593
Uniprot IDs		A0A0A0MS29 A1MAC2 Q9GZY8	Q9Y320
PDB IDs			2DJ0
Enriched GO Terms of Interacting Partners?
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