CLDND1 and CXCR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDND1	CXCR1
Description		claudin domain containing 1	C-X-C motif chemokine receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Surface Integral Component Of Membrane Apical Plasma Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane
	Molecular Function	Protein Binding	Interleukin-8 Receptor Activity G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding Interleukin-8 Binding
	Biological Process		Dendritic Cell Chemotaxis Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Neutrophil Chemotaxis Receptor Internalization Interleukin-8-mediated Signaling Pathway Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ketoprofen
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245)	Basophil count ( 32888494) Diffusing capacity of carbon monoxide ( 30694715) Idiopathic intracranial hypertension ( 29608535) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 29403010) Smooth-surface caries ( 23470693) White blood cell count ( 29403010)
Interacting Genes		5 interacting genes: CXCR1 DRD2 GPR61 MTNR1B ZDHHC4	21 interacting genes: ADRA1A CDK1 CLDND1 CXCL1 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCR2 FATE1 GNA14 GNA15 GNAI2 IGFBP5 PDCD6IP PPBP TRARG1 TUBA1A TUBA4A UBE2C
Entrez ID		56650	3577
HPRD ID		12822	00908
Ensembl ID		ENSG00000080822	ENSG00000163464
Uniprot IDs		A0A0R4J2F2 Q9NY35	P25024
PDB IDs			1ILP 1ILQ 2LNL
Enriched GO Terms of Interacting Partners?
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