CXCR1 and CLDND1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CXCR1	CLDND1
Description		C-X-C motif chemokine receptor 1	claudin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane	Cell Surface Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Interleukin-8 Receptor Activity G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding Interleukin-8 Binding	Protein Binding
	Biological Process	Dendritic Cell Chemotaxis Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Neutrophil Chemotaxis Receptor Internalization Interleukin-8-mediated Signaling Pathway Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs		Ketoprofen
Diseases
GWAS		Basophil count ( 32888494) Diffusing capacity of carbon monoxide ( 30694715) Idiopathic intracranial hypertension ( 29608535) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 29403010) Smooth-surface caries ( 23470693) White blood cell count ( 29403010)	Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		21 interacting genes: ADRA1A CDK1 CLDND1 CXCL1 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCR2 FATE1 GNA14 GNA15 GNAI2 IGFBP5 PDCD6IP PPBP TRARG1 TUBA1A TUBA4A UBE2C	5 interacting genes: CXCR1 DRD2 GPR61 MTNR1B ZDHHC4
Entrez ID		3577	56650
HPRD ID		00908	12822
Ensembl ID		ENSG00000163464	ENSG00000080822
Uniprot IDs		P25024	A0A0R4J2F2 Q9NY35
PDB IDs		1ILP 1ILQ 2LNL
Enriched GO Terms of Interacting Partners?
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