INAVA and CYTH3

Number of citations of the paper that reports this interaction (PubMedID 30355448)
5

Data Source:
BioGRID (pull down)

		INAVA	CYTH3
Description		innate immunity activator	cytohesin 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Protein Ubiquitination Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Adherens Junction Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Intestinal Epithelial Structure Maintenance Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Reactive Oxygen Species Biosynthetic Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Celiac disease ( 30572963)	Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)
Interacting Genes		3 interacting genes: CYTH1 CYTH2 CYTH3	12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN
Entrez ID		55765	9265
HPRD ID		07712	05469
Ensembl ID		ENSG00000163362	ENSG00000008256
Uniprot IDs		Q3KP66	O43739
PDB IDs			4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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