CYTH3 and IFI35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYTH3	IFI35
Description		cytohesin 3	interferon induced protein 35
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Extracellular Space Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Innate Immune Response Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Intra-Golgi traffic	Interferon alpha/beta signaling
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)	Coronary artery disease ( 29212778)
Interacting Genes		12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN	12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63
Entrez ID		9265	3430
HPRD ID		05469	02844
Ensembl ID		ENSG00000008256	ENSG00000068079
Uniprot IDs		O43739	P80217
PDB IDs		4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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