MNS1 and THOC7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MNS1	THOC7
Description		meiosis specific nuclear structural 1	THO complex 7
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Intermediate Filament Axoneme Motile Cilium Sperm Flagellum	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Sperm Axoneme Assembly Cilium Organization Positive Regulation Of Cilium Assembly Meiotic Cell Cycle Left/right Axis Specification	MRNA Processing MRNA Export From Nucleus RNA Splicing Viral MRNA Export From Host Cell Nucleus
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Body shape index ( 34021172) Chronic lymphocytic leukemia ( 26956414 23770605) Clozapine-induced agranulocytosis ( 25187353) Hematology traits ( 30576415) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Neutrophil count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 29483656 30285260) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: CCND3 CDR2 CEP63 DISC1 EP400 EWSR1 FCHSD2 GIGYF1 IQCB1 KDM1A KIAA0753 KRT34 KRT75 PICK1 RSPH14 SNX32 STMN3 THOC7 TNNI1 TNNI2 TRIM54 TXLNB USHBP1 ZMYND12	11 interacting genes: CCDC146 CHD3 CKAP4 GOT2 MED22 MED8 MNS1 NDC80 NIF3L1 SMARCD1 THOC5
Entrez ID		55329	80145
HPRD ID		10967	17632
Ensembl ID		ENSG00000138587	ENSG00000163634
Uniprot IDs		B3KQ70 Q8NEH6	A0A024R332 A0A5S6STF9 Q6I9Y2
PDB IDs			7APK
Enriched GO Terms of Interacting Partners?
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