MNS1 and EP400

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MNS1	EP400
Description		meiosis specific nuclear structural 1	E1A binding protein p400
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Intermediate Filament Axoneme Motile Cilium Sperm Flagellum	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Identical Protein Binding	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP-dependent Chromatin Remodeler Activity Protein Antigen Binding
	Biological Process	Sperm Axoneme Assembly Cilium Organization Positive Regulation Of Cilium Assembly Meiotic Cell Cycle Left/right Axis Specification	Histone H4 Acetylation Histone H2A Acetylation
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones
Drugs
Diseases
GWAS		Body shape index ( 34021172) Chronic lymphocytic leukemia ( 26956414 23770605) Clozapine-induced agranulocytosis ( 25187353) Hematology traits ( 30576415) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		24 interacting genes: CCND3 CDR2 CEP63 DISC1 EP400 EWSR1 FCHSD2 GIGYF1 IQCB1 KDM1A KIAA0753 KRT34 KRT75 PICK1 RSPH14 SNX32 STMN3 THOC7 TNNI1 TNNI2 TRIM54 TXLNB USHBP1 ZMYND12	13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT
Entrez ID		55329	57634
HPRD ID		10967	09378
Ensembl ID		ENSG00000138587	ENSG00000183495
Uniprot IDs		B3KQ70 Q8NEH6	Q96L91
PDB IDs
Enriched GO Terms of Interacting Partners?
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