AGPAT5 and PSCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AGPAT5	PSCA
Description		1-acylglycerol-3-phosphate O-acyltransferase 5	prostate stem cell antigen
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Acyltransferase Activity	Acetylcholine Receptor Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Acylglycerol Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity
Pathways		Synthesis of PA	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HDL cholesterol ( 30275531) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Serum alkaline phosphatase levels ( 33547301)	Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Schizophrenia ( 33169155) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)
Interacting Genes		6 interacting genes: CREB3L1 CYB561A3 PSCA SCN3B TMX2 UBQLN1	43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6
Entrez ID		55326	8000
HPRD ID		12438	03919
Ensembl ID		ENSG00000155189	ENSG00000167653
Uniprot IDs		A0A024R640 Q9NUQ2	D3DWI6 O43653
PDB IDs
Enriched GO Terms of Interacting Partners?
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