PSCA and SYS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PSCA	SYS1
Description		prostate stem cell antigen	SYS1 golgi trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome	Trans-Golgi Network Cytosol Integral Component Of Golgi Membrane Trans-Golgi Network Membrane
	Molecular Function	Acetylcholine Receptor Binding	Protein Binding
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity	Golgi To Endosome Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Schizophrenia ( 33169155) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)	Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35C2 TM4SF19 TMEM248 TNFSF14
Entrez ID		8000	90196
HPRD ID		03919
Ensembl ID		ENSG00000167653	ENSG00000204070
Uniprot IDs		D3DWI6 O43653	Q8N2H4
PDB IDs
Enriched GO Terms of Interacting Partners?
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